Predisposition to spina bifida.

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چکیده

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Predisposition to spina bifida: Search for a relation to maternal gastric acid secretion.

The peak acid output of the stomach in a group of 71 mothers of spina bifida children and in 71 matched controls was estimated indirectly by the serum level of group I pepsinogens. The mean levels did not differ significantly, suggesting that the conjectured teratogen is not specially acid-labile. The variance was significantly higher in index subjects than in controls, but the interpretation o...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1978

ISSN: 1468-6244

DOI: 10.1136/jmg.15.6.487